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Minibrain Lab

2024






"Three-dimensional human neural culture on a chip recapitulating neuroinflammation and neurodegeneration"


Minibrain Lab








"A 3D human triculture system modeling neurodegeneration and neuroinflammation in Alzheimer’s disease"


A dynamic entrepreneur exploring interdisciplinary areas: neuroengineering, quantum biophysics, nanobiosciences, and neurosciences utilizing engineering technologies and biological/medical knowledge 


Research Areas

Human Minibrains

The human minibrain includes brain cells in a microfluidic chip. In this lab, not only the brain but also as a gut-brain axis, blood-brain barrier and blood vessels are studied using microfluidic chips.

 

Neuromodulators

By investigating and researching various signals from neurons and other cells, our lab does research on neurodegenerative diseases and dementia.

Neurological Disorders

Our lab is using microfluidic chips to study neurodegenerative diseases and dementia. These are also have used to study for dementia treatment.

News

  • Xiahui Zhu, Hansang Cho. ADPD 2025 Conference, April 1-5th, 2025 in Vienna, Austria
  • Biomicrofluidics Best Paper Award, The 28th International Conference on Miniaturized Systems for Chemistry and Life Sciences - Micro-Total Analysis Systems (µTAS 2024) - Minh
  • CBMS Student/Young Researcher Grant from uTAS - Minh
  • V.T.A. Tran, L.P. Lee, H. Cho, "the Society for Neuroscience’s 52nd annual meeting" (Neuroscience 2024), Chicago, Il, USA, Oct. 5-9, 2024
  • K.V. Do, M. Tran, Y.J. Kang, T. Huynh, C. Heo, H. Cho, "the Society for Neuroscience’s 52nd annual meeting" (Neuroscience 2024), Chicago, Il, USA, Oct. 5-9, 2024
  • Minh Tran, Chaeyeon Been, Van Thi Ai Tran, Luke P. Lee, Hansang Cho. ” 2024 The 28th International Conference on Miniaturized Systems for Chemistry and Life Sciences - Micro-Total Analysis Systems" (μTAS), October 13-17, 2024 in Montreal, Canada (Oral presentation)
  • Y.N. Diep, X. Zhu, H. Cho, "7th Tissue Engineering and Regenerative Medicine World Congress 2024" (TERMIS-WC 2024), June 25-28, 2024, Seattle, WA, USA (oral presentation) 
  • M. Tran, H. Cho, "Microphysiological systems (MPS) World Submit", June 10-14, 2024, Seattle, WA, USA(oral presentation)

Publications

“Microbiome-derived indole-3-lactic acid reduces amyloidopathy through aryl-hydrocarbon receptor activation”


Brain Behavior and Immunity 2024, 122:568

 
“Microglia gravitate toward amyloid plaques surrounded by externalized phosphatidylserine via TREM2” 
Advanced Science 2024, 11:2400064

 

Announcement

Contact

Position opening for graduate students
2066 Seobu-ro, Jangan-gu / #86702 N Center
Suwon-si, Gyeonggi-do, 16419, Korea
Email: h.cho@g.skku.edu
Phone: +82-31-299-4792